Lumbar spinal malignant peripheral nerve sheath tumor arising from a benign neurofibroma
نویسندگان
چکیده
منابع مشابه
Lumbar spinal malignant peripheral nerve sheath tumor arising from a benign neurofibroma
We present the case of a 27-year-old man who had a soft-tissue lumbar spine mass causing back, abdominal, and groin pain. Imaging showed the lesion filling the right neural foramen, invading the anterior L2 vertebral body and both pedicles, and protruding into the central canal, causing compression of the thecal sac. The final pathologic diagnosis was a malignant peripheral nerve sheath tumor, ...
متن کاملMalignant Peripheral Nerve Sheath Tumour Arising From Solitary Sclerotic Neurofibroma.
Neurofibroma is a benign neoplasm of the peripheral nerve, which occurs as multiple tumours in neurofibromatosis type 1 (NF1) or as a solitary tumour with no association with NF1. Malignant change is sometimes reported in neurofibroma in NF1, but there are few reports of malignant transformation of solitary neurofibroma. We report here a case of malignant change in a solitary sclerotic neurofib...
متن کاملMalignant Peripheral Nerve Sheath Tumor Arising from Neurofibromatosis
Neurofibromatosis type 1 (NF 1) is an inherited autosomal dominant disorder with an estimated incidence of 1 in 2,500 to 3,000 live births [1]. Neurofibromas are benign peripheral nerve sheath tumors developed from the proliferation of fibroblasts and Schwann cells. Wallac [2] categorized neurofibromas into four types: cutaneous neurofibromas of the epidermis or dermis, subcutaneous neurofibrom...
متن کاملIntrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features
Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...
متن کاملMalignant peripheral nerve sheath tumour arising within neurofibroma. An immunohistochemical analysis in the comparison between benign and malignant components.
AIMS To compare the expression of immunohistochemical variables between benign and malignant components of malignant peripheral nerve sheath tumour (MPNST) arising within neurofibroma. METHODS Eight cases of MPNST arising within a neurofibroma, associated with neurofibromatosis type 1 (NF1), were studied. The areas of MPNST and neurofibroma were compared immunohistochemically with regard to t...
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ژورنال
عنوان ژورنال: Radiology Case Reports
سال: 2010
ISSN: 1930-0433
DOI: 10.2484/rcr.v5i3.417